Noninvasive test for tuberculosis detection among primates

Tiffany M. Wolf; Lawrence Mugisha; Fernanda Miyagaki Shoyama; Melanie J. O ’ Malley; Joanne L. Flynn; Benon Asiimwe; Dominic A. Travis; Randall S. Singer; Srinand Sreevatsan

doi:10.3201/eid2103.140052

Noninvasive test for tuberculosis detection among primates

Tiffany M. Wolf, Lawrence Mugisha, Fernanda Miyagaki Shoyama, Melanie J. O ’ Malley, Joanne L. Flynn, Benon Asiimwe, Dominic A. Travis, Randall S. Singer, Srinand Sreevatsan

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplifcation of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.

Original language	English (US)
Pages (from-to)	468-470
Number of pages	3
Journal	Emerging infectious diseases
Volume	21
Issue number	3
DOIs	https://doi.org/10.3201/eid2103.140052
State	Published - 2015

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© 2015, Centers for Disease Control and Prevention (CDC). All rights reserved.

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title = "Noninvasive test for tuberculosis detection among primates",

abstract = "Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplifcation of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.",

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AU - Mugisha, Lawrence

AU - Shoyama, Fernanda Miyagaki

AU - O ’ Malley, Melanie J.

AU - Flynn, Joanne L.

AU - Asiimwe, Benon

AU - Travis, Dominic A.

AU - Singer, Randall S.

AU - Sreevatsan, Srinand

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AB - Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplifcation of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.

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Noninvasive test for tuberculosis detection among primates

Abstract

Bibliographical note

UN SDGs

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