Novel biocatalysis by database mining

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Abstract

Broad-based adoption of biocatalytic methods will require widely available database tools, analogous to previous efforts compiling information for the facilitation of chemical synthesis. The analog to chemical reagents are enzymes. The analog to chemical synthetic routes are metabolic pathways. The free on-line database BRENDA exemplifies efforts to compile relevant information on enzymes for biocatalytic purposes. Likewise, the University of Minnesota Biocatalysis/Biodegradation Database focuses on novel enzymes and metabolic pathways useful in environmental and industrial biotechnology. The development of biocatalytic protocols will be facilitated by the increasing availability of well-curated database information on enzymatic enantioselectivity and capabilities for transforming disparate chemical functional groups.

Original languageEnglish (US)
Pages (from-to)280-284
Number of pages5
JournalCurrent opinion in biotechnology
Volume15
Issue number4
DOIs
StatePublished - Aug 2004

Bibliographical note

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

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