Novel metrics to measure the effect of additive inputs on the activity of sensory system neurons

Maryam Hosseini; Gerardo Rodriguez; Hongsun Guo; Hubert Lim; Eric Plourde

doi:10.1109/EMBC.2019.8857622

Novel metrics to measure the effect of additive inputs on the activity of sensory system neurons

Maryam Hosseini, Gerardo Rodriguez, Hongsun Guo, Hubert Lim, Eric Plourde

Otolaryngology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Sensory systems, such as the visual or auditory system, are highly non linear. It is therefore not easy to predict the effect of additive inputs on the spiking activity of related brain structures. Here, we propose two metrics to study the effect of additive covariates on the spiking activity of neurons. These metrics are directly obtained from a generalized linear model. We apply these metrics to the study of the effect of additive input audio noise on the spiking activity of neurons in the auditory system. To do so, we combine clean vocalisations with natural stationary or non-stationary noises and record activity in the auditory system while presenting the noisy vocalisations. We found that non-stationary noise has a greater effect on the neural activity than stationary noise. We observe that the results, obtained using the proposed metrics, is more consistent with current knowledge in auditory neuroscience than the results obtained when using a common metric from the literature, the extraction index.

Original language	English (US)
Title of host publication	2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	5141-5145
Number of pages	5
ISBN (Electronic)	9781538613115
DOIs	https://doi.org/10.1109/EMBC.2019.8857622
State	Published - Jul 2019
Event	41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 - Berlin, Germany Duration: Jul 23 2019 → Jul 27 2019

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Conference

Conference	41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
Country/Territory	Germany
City	Berlin
Period	7/23/19 → 7/27/19

Bibliographical note

Funding Information:
This work was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC)

Publisher Copyright:
© 2019 IEEE.

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10.1109/EMBC.2019.8857622

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Hosseini, M., Rodriguez, G., Guo, H., Lim, H., & Plourde, E. (2019). Novel metrics to measure the effect of additive inputs on the activity of sensory system neurons. In 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 (pp. 5141-5145). Article 8857622 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2019.8857622

Novel metrics to measure the effect of additive inputs on the activity of sensory system neurons. / Hosseini, Maryam; Rodriguez, Gerardo; Guo, Hongsun et al.
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. p. 5141-5145 8857622 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hosseini, M, Rodriguez, G, Guo, H, Lim, H & Plourde, E 2019, Novel metrics to measure the effect of additive inputs on the activity of sensory system neurons. in 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019., 8857622, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., pp. 5141-5145, 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019, Berlin, Germany, 7/23/19. https://doi.org/10.1109/EMBC.2019.8857622

Hosseini M, Rodriguez G, Guo H, Lim H, Plourde E. Novel metrics to measure the effect of additive inputs on the activity of sensory system neurons. In 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Institute of Electrical and Electronics Engineers Inc. 2019. p. 5141-5145. 8857622. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2019.8857622

Hosseini, Maryam ; Rodriguez, Gerardo ; Guo, Hongsun et al. / Novel metrics to measure the effect of additive inputs on the activity of sensory system neurons. 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 5141-5145 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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Novel metrics to measure the effect of additive inputs on the activity of sensory system neurons

Abstract

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