Office-based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: A pilot study

Holly Boyer, Patricia Fernandes, Olga Duran, David Hunter, George Goding

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Background: The aim of this pilot study is to evaluate office-based sclerotherapy using sodium tetradecyl sulfate (STS) for epistaxis due to hereditary hemorrhagic telangiectasias (HHT). Patients with HHT suffer from unpredictable, recurrent, severe nasal bleeding necessitating emergency care, nasal packing, blood transfusions, and invasive procedures. Methods: In this retrospective study 7 patients with a history of treatment for recurrent epistaxis due to HHT were treated in an office-based setting with intralesional injection of STS. Treatment results were evaluated using a questionnaire. All patients had undergone multiple prior procedures attempting to control epistaxis. Results: Patients had an average of 5 sclerotherapy treatments for HHT. Patients were treated using topical and/or local anesthesia with no reports of discomfort. Bleeding requiring intervention did not occur during the procedures. After the procedure all patients (100%) reported significantly less frequent and less severe nasal bleeding. A total of 83% reported that their need for nasal packing was reduced. All patients were willing to undergo the same treatment again. No complications such as perforation, crusting, or foul smell were reported. Conclusion: This is the first clinical experience demonstrating that office-based sclerotherapy with STS is a safe, tolerable, and useful alternative for the treatment of epistaxis due to HHT.

Original languageEnglish (US)
Pages (from-to)319-323
Number of pages5
JournalInternational Forum of Allergy and Rhinology
Volume1
Issue number4
DOIs
StatePublished - Jul 1 2011

Keywords

  • Epistaxis
  • Hereditary hemorrhagic telangiectasia
  • Osler-Weber-Rendu syndrome
  • Sclerotherapy
  • Sodium tetradecyl sulfate

Fingerprint Dive into the research topics of 'Office-based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: A pilot study'. Together they form a unique fingerprint.

Cite this