Oncologic and functional outcomes of partial laryngeal surgery for intermediate-stage laryngeal cancer

Emiro Caicedo-Granados, Daniel M. Beswick, Apostolos Christopoulos, Diana E. Cunningham, Ali Razfar, James P. Ohr, Dwight E. Heron, Robert L. Ferris

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Objective. To evaluate the oncologic and functional outcomes of partial laryngeal surgery (PLS) using transoral laser microsurgery (TLM) and supracricoid laryngectomy (SCL) in patients with intermediate-stage laryngeal squamous cell carcinoma (LSCC). Study Design. Historical cohort study. Setting. Single tertiary care center. Subjects and Methods. Retrospective review of oncologic and functional outcomes in intermediate-stage (T2-3/N0-1, stage II and III) LSCC patients who underwent TLM or SCL from 1998 to 2010. Results. Sixty patients were included, of whom 28 (47%) underwent TLM and 32 (53%) underwent SCL. For the entire cohort, 2- and 5-year probabilities were 86.2% (95% confidence interval [CI], 73.0%-93.2%) and 72.9% (95% CI, 52.4%-85.6%), respectively, for overall survival (OS) and 79.3% (95% CI, 65.6%-88.0%) and 62.4% (95% CI, 41.9%- 77.4%), respectively, for recurrence-free survival (RFS). There was no difference between the TLM and SCL cohorts in OS (P = .542) or RFS (P = .483). More than 75% of patients avoided adjuvant therapy. Communication Scale and Functional Outcome Swallowing Scale scores at median follow-up of 33 months were 2 or better in 97% and 91% of patients, respectively, reflecting functional voice and swallowing postoperatively. Eighty-eight percent of patients retained a functional larynx. Conclusion. PLS provides excellent oncologic and functional outcomes for intermediate-stage LSCC and should be considered an alternative to chemoradiation or total laryngectomy in selected patients.

Original languageEnglish (US)
Pages (from-to)235-242
Number of pages8
JournalOtolaryngology - Head and Neck Surgery (United States)
Issue number2
StatePublished - Feb 2013

Bibliographical note

Copyright 2013 Elsevier B.V., All rights reserved.


  • Laryngeal cancer
  • Supracricoid laryngectomy
  • Transoral laser microsurgery


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