TY - JOUR
T1 - Operator-interactive method for simultaneous measurement of left and right ventricular volumes and ejection fraction by tomographic electrocardiography-gated blood pool radionuclide ventriculography
AU - Clements, Ian P.
AU - Brinkmann, Benjamin
AU - Mullan, Brian P.
AU - O'Connor, Michael K.
AU - Breen, Jerome F.
AU - McGregor, Christopher G.A.
PY - 2006/1
Y1 - 2006/1
N2 - Background. A method that uses single photon emission computed tomography (SPECT) equilibrium radionuclide angiocardiography (ERNA) to measure right ventricular (RV) and left ventricular (LV) volumes (in milliliters) and ejection fraction (EF) is described. Methods and Results. We recorded 35 paired SPECT ERNA and electron beam computed tomography (EBCT) cardiac studies in 27 patients; for comparison with EBCT, a method for measurement of RV and LV volumes and EF with SPECT ERNA was developed in 18 paired studies and was validated and assessed for reproducibility in 17. Validation indicated that SPECT ERNA and EBCT were similar for measurement of RV volume (end-systolic and end-diastolic volumes in a combined analysis) and EF (180 ± 74 mL vs 182 ± 80 mL and 0.44 ± 0.11 vs 0.43 ± 0.11, respectively) and for measurement of LV volume and EF (88 ± 36 mL vs 84 ± 43 mL and 0.53 ± 0.081 vs 0.59 ± 0.07, respectively). The SPECT ERNA method was quite reproducible. Conclusions. RV and LV volumes and EF can be measured readily via SPECT ERNA.
AB - Background. A method that uses single photon emission computed tomography (SPECT) equilibrium radionuclide angiocardiography (ERNA) to measure right ventricular (RV) and left ventricular (LV) volumes (in milliliters) and ejection fraction (EF) is described. Methods and Results. We recorded 35 paired SPECT ERNA and electron beam computed tomography (EBCT) cardiac studies in 27 patients; for comparison with EBCT, a method for measurement of RV and LV volumes and EF with SPECT ERNA was developed in 18 paired studies and was validated and assessed for reproducibility in 17. Validation indicated that SPECT ERNA and EBCT were similar for measurement of RV volume (end-systolic and end-diastolic volumes in a combined analysis) and EF (180 ± 74 mL vs 182 ± 80 mL and 0.44 ± 0.11 vs 0.43 ± 0.11, respectively) and for measurement of LV volume and EF (88 ± 36 mL vs 84 ± 43 mL and 0.53 ± 0.081 vs 0.59 ± 0.07, respectively). The SPECT ERNA method was quite reproducible. Conclusions. RV and LV volumes and EF can be measured readily via SPECT ERNA.
KW - Ejection fraction
KW - Electron beam computed tomography
KW - Equilibrium radionuclide angiocardiography
KW - Single photon emission computed tomography
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U2 - 10.1016/j.nuclcard.2005.12.005
DO - 10.1016/j.nuclcard.2005.12.005
M3 - Article
C2 - 16464717
AN - SCOPUS:32044465580
SN - 1071-3581
VL - 13
SP - 50
EP - 63
JO - Journal of Nuclear Cardiology
JF - Journal of Nuclear Cardiology
IS - 1
ER -
