Opioid peptide effects on feeding in rabbits

Blake A. Gosnell; James M. Lipton

doi:10.1016/0196-9781(86)90089-6

Opioid peptide effects on feeding in rabbits

Blake A. Gosnell, James M. Lipton

Food Science and Nutrition

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

The food intake of rabbits was measured after intracerebroventricular injections of several opioid agonists and naloxone. The preferential kappa agonist dynorphin A increased intake, while naloxone, [D-Ser²,Leu⁵]enkephalin-Thr⁶ and Tyr-D-Ala-Gly-(Me)Phe-Gly-ol reduced intake or had no effect. These results suggest that kappa receptors have a role in the control of feeding in rabbits.

Original language	English (US)
Pages (from-to)	745-747
Number of pages	3
Journal	Peptides
Volume	7
Issue number	5
DOIs	https://doi.org/10.1016/0196-9781(86)90089-6
State	Published - 1986

Keywords

Food intake
Naloxone
Opioids
Rabbits

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abstract = "The food intake of rabbits was measured after intracerebroventricular injections of several opioid agonists and naloxone. The preferential kappa agonist dynorphin A increased intake, while naloxone, [D-Ser2,Leu5]enkephalin-Thr6 and Tyr-D-Ala-Gly-(Me)Phe-Gly-ol reduced intake or had no effect. These results suggest that kappa receptors have a role in the control of feeding in rabbits.",

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AU - Lipton, James M.

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AB - The food intake of rabbits was measured after intracerebroventricular injections of several opioid agonists and naloxone. The preferential kappa agonist dynorphin A increased intake, while naloxone, [D-Ser2,Leu5]enkephalin-Thr6 and Tyr-D-Ala-Gly-(Me)Phe-Gly-ol reduced intake or had no effect. These results suggest that kappa receptors have a role in the control of feeding in rabbits.

KW - Food intake

KW - Naloxone

KW - Opioids

KW - Rabbits

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ER -

Opioid peptide effects on feeding in rabbits

Abstract

Keywords

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