Oral fibroma with HPV-associated epithelial dysplasia: Even in fibromas you should look for the unexpected

Prokopios Argyris, Ioannis G Koutlas

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Fibromas are the most common soft tissue lesions of the oral cavity and are generally attributed to trauma. Koilocytic dysplasia refers to human papillomavirus (HPV)-related epithelial cytopathic effect. Koilocytic dysplasia is considered neoplastic. Herein, we report a case of oral fibroma with HPV-induced dysplastic changes of the surface epithelium confirmed by immunohistochemical stains for p16 and p53 as well as HPV in situ hybridization.

Original languageEnglish (US)
Pages (from-to)248-249
Number of pages2
JournalInternational Journal of Surgical Pathology
Volume22
Issue number3
DOIs
StatePublished - May 2014

Keywords

  • fibroma
  • HPV
  • koilocytic dysplasia
  • p16
  • p53

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