Oxalosis-induced bone disease: A complication of transplantation and prolonged survival in primary hyperoxaluria. Report of a case

A. Breed, R. Chesney, A. Friedman, E. Gilbert, L. Langer, R. Lattoraca

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

The authors report the case of a child with Type-I primary hyperoxaluria who, at the time of writing, had survived for sixty-one months after a renal transplant and had an unusual bone disorder. She had prolonged hypercalcemia, unaffected by a successful subtotal parathyroidectomy, and progressive, universal, pathological changes in bone, leading to several pathological fractures. A striking clinical feature was the bulbous enlargement of the tips of some of the fingers with extrusion of calcium oxalate from the nail beds. The authors present the findings from radiographic, histological, and electron microscopic studies of the bones of this patient.

Original languageEnglish (US)
Pages (from-to)310-316
Number of pages7
JournalUnknown Journal
Volume63
Issue number2
DOIs
StatePublished - Jan 1 1981

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