Papers: Effect of cross-fostering on transfer of maternal immunity to Mycoplasma hyopneumoniae to piglets

M. Bandrick, M. Pieters, C. Pijoan, S. K. Baidoo, T. W. Molitor

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The aim of this study was to assess the effect of cross-fostering on transfer of maternal Mycoplasma hyopneumoniae-specific humoral and cell-mediated immunity (CMI) from gilts to piglets. Cross-fostering, carried out within gilt pairs, was based on the gilts' M hyopneumoniae vaccination status in accordance with the following scheme: six pairs of vaccinated gilt x non-vaccinated gilt (V x N); five pairs of non-vaccinated gilt x vaccinated gilt (N x V); and five pairs of vaccinated gilt x vaccinated gilt (V x V). The piglets were cross-fostered at 0, six, 12 or 20 hours after birth. Two piglets per gilt per time point were cross-fostered (that is, eight piglets per gilt were moved) and the remaining piglets served as non-cross-fostered controls. In addition, four litters served as non-cross-fostered controls. A maximum of 10 piglets per gilt were sampled. The piglets' M hyopneumoniae-specific humoral immunity was assessed by ELISA and their CMI was assessed by delayed-type hypersensitivity testing. M hyopneumoniae-specific antibodies were detected in non-crossfostered piglets from vaccinated dams and from piglets cross-fostered within the V x N gilt pair at six hours or more, and within the V x V gilt pair at all time points. Piglets cross-fostered within the N x V gilt pair had detectable M hyopneumoniae-specific antibodies only if they had been moved within six hours of birth. The transfer of M hyopneumoniae-specific CMI to piglets appeared to be source-dependent, and was detected only in piglets maintained on their vaccinated dams for at least 12 hours after birth.

Original languageEnglish (US)
Pages (from-to)100
Number of pages1
JournalVeterinary Record
Volume168
Issue number4
DOIs
StatePublished - Jan 29 2011

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