TY - JOUR
T1 - Pathogenesis and pathology of graft-vs.-host disease
AU - Wagner, John E.
AU - Vogelsang, Georgia B.
AU - Beschorner, William E.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Over the past decade, there has been a significant increase in the number of patients with a variety of malignant and nonmalignant disorders referred for bone marrow transplantation. Despite numerous advances in the care of such patients after allogeneic bone marrow transplantation, acute and chronic graft-vs.-host disease continues to be a prinicipal cause of morbidity and mortality. In this article, we will present an overview of the pathogenesis, clinical presentation, and pathological manifestations of these two major complications.
AB - Over the past decade, there has been a significant increase in the number of patients with a variety of malignant and nonmalignant disorders referred for bone marrow transplantation. Despite numerous advances in the care of such patients after allogeneic bone marrow transplantation, acute and chronic graft-vs.-host disease continues to be a prinicipal cause of morbidity and mortality. In this article, we will present an overview of the pathogenesis, clinical presentation, and pathological manifestations of these two major complications.
KW - Bone marrow transplantation
KW - Graft-vs.-host disease
KW - Pathogenesis
KW - Pathology
UR - http://www.scopus.com/inward/record.url?scp=0024335863&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024335863&partnerID=8YFLogxK
M3 - Article
C2 - 2665549
AN - SCOPUS:0024335863
SN - 0192-8562
VL - 11
SP - 196
EP - 212
JO - American Journal of Pediatric Hematology/Oncology
JF - American Journal of Pediatric Hematology/Oncology
IS - 2
ER -
