TY - JOUR
T1 - Pediatric non-Hodgkin lymphoma
AU - Gross, Thomas G.
AU - Termuhlen, Amanda M.
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2008/7
Y1 - 2008/7
N2 - Non-Hodgkin lymphoma (NHL) accounts for 7% of cancer in children and adolescents in the United States, or approximately 1000 cases annually. NHL in the pediatric population differs from that observed in adult patients with respect to staging systems, histologic subtypes of disease, treatment, and outcomes. Although more than 90% of pediatric NHL is of high-grade histology, more than 80% of patients achieve long-term event-free survival with modern therapy. This review focuses on current treatments for pediatric NHL and some of the differences between NHL observed in pediatric and adult patients.
AB - Non-Hodgkin lymphoma (NHL) accounts for 7% of cancer in children and adolescents in the United States, or approximately 1000 cases annually. NHL in the pediatric population differs from that observed in adult patients with respect to staging systems, histologic subtypes of disease, treatment, and outcomes. Although more than 90% of pediatric NHL is of high-grade histology, more than 80% of patients achieve long-term event-free survival with modern therapy. This review focuses on current treatments for pediatric NHL and some of the differences between NHL observed in pediatric and adult patients.
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U2 - 10.1007/s11899-008-0024-8
DO - 10.1007/s11899-008-0024-8
M3 - Review article
C2 - 20425462
AN - SCOPUS:47549098845
SN - 1558-8211
VL - 3
SP - 167
EP - 173
JO - Current Hematologic Malignancy Reports
JF - Current Hematologic Malignancy Reports
IS - 3
ER -
