Peptide YY (PYY), a poteny orexigenic agent

John E. Morley; Allen S. Levine; Martha Grace; Julie Kneip

doi:10.1016/0006-8993(85)91490-8

Peptide YY (PYY), a poteny orexigenic agent

John E. Morley, Allen S. Levine, Martha Grace, Julie Kneip

Medicine - Administration

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121 Scopus citations

Abstract

Peptide YY (PYY) enhances feeding and drinking more potently than does neuropeptide Y after central administration. Chronic administration of PYY every 6 h for 48 h causes massive food ingestion. Tolerance to this effect of PYY does not appear to develop. This data suggests that PYY is one of the most potent orexigenic substances yet to be identified. PYY may play a role in the pathogenesis of bulimic syndromes.

Original language	English (US)
Pages (from-to)	200-203
Number of pages	4
Journal	Brain Research
Volume	341
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(85)91490-8
State	Published - Aug 19 1985

Bibliographical note

Funding Information:
We acknowledge the excellent secretarial assistance of J. Tallman. The studies reported here were supported by the Medical Research Funds of the Veterans Administration.

Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.

Keywords

bulimia
drinking
food intake
peptide YY

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abstract = "Peptide YY (PYY) enhances feeding and drinking more potently than does neuropeptide Y after central administration. Chronic administration of PYY every 6 h for 48 h causes massive food ingestion. Tolerance to this effect of PYY does not appear to develop. This data suggests that PYY is one of the most potent orexigenic substances yet to be identified. PYY may play a role in the pathogenesis of bulimic syndromes.",

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AU - Kneip, Julie

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AB - Peptide YY (PYY) enhances feeding and drinking more potently than does neuropeptide Y after central administration. Chronic administration of PYY every 6 h for 48 h causes massive food ingestion. Tolerance to this effect of PYY does not appear to develop. This data suggests that PYY is one of the most potent orexigenic substances yet to be identified. PYY may play a role in the pathogenesis of bulimic syndromes.

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Peptide YY (PYY), a poteny orexigenic agent

Abstract

Bibliographical note

Keywords

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