Percutaneous approaches to mitral valve regurgitation

Stefan C Bertog, J. Franke, D. H. Steinberg, N. Wunderlich, H. Sievert

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Mitral regurgitation is a common problem associated with significant morbidity and mortality. Mitral valve surgery has been the treatment of choice for symptomatic patients with severe mitral regurgitation or asymptomatic patients with high-risk clinical features. However, a significant number of patients remain untreated related mainly due to a projected high surgical risk. Therefore, alternative percutaneous treatments including indirect annuloplasty, which takes advantage of the coronary sinus, and direct annuloplasty have recently been explored. Most recently, promising results of the first randomized trial comparing conventional mitral valve surgery to percutaneous therapy with a clip creating a double orifice much like the surgical Alfieri approach have been presented. Finally, percutaneous mitral valve replacement in an animal model has been pursued. This review serves to familiarize the reader with some anatomical concepts and devices for percutaneous mitral repair.

Original languageEnglish (US)
Pages (from-to)172-182
Number of pages11
Issue number2
StatePublished - Mar 1 2012


  • Mitral valve annuloplasty
  • Mitral valve regurgitation
  • Mitral valve repair
  • Review

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