PET studies of somatosensory processing of light touch

Matthew C. Hagen, Jose V Pardo

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

The studies discussed in this report investigate the neural mechanisms involved in processing a light tactile stimulus as measured by positron emission tomography (PET). This light tactile stimulus (a 2-Hz tap with a von Frey hair) produced a significant increase in regional cerebral blood flow (rCBF) in contralateral primary somatosensory cortex (SI) and bilateral secondary somatosensory cortex (SII), with a larger response in the side contralateral to the stimulus. Light tactile stimulation also produced activity in multiple discrete areas in the human inferior parietal lobule (IPL), which we believe to comprise a region homologous to the monkey area 7b or feline tertiary somatosensory cortex (SIII). Directing attention to the tactile stimulus increased blood flow to SIII and activated a right-lateralized cortical network, regardless of the side of body stimulated. Directed attention to the stimulus decreased blood flow to visual cortex, but minimally modulated SI rCBF.

Original languageEnglish (US)
Pages (from-to)133-140
Number of pages8
JournalBehavioural Brain Research
Volume135
Issue number1-2
DOIs
StatePublished - Sep 20 2002

Bibliographical note

Funding Information:
We would like to thank Joel T. Lee and Michele R. Spoont, as well as the rest of the staff of the Cognitive Neuroimaging Unit, for their assistance with data collection and analysis. We would also like to thank our subjects for their participation in these experiments. We would like to acknowledge the Department of Veterans Affairs for support of this work. M.H. is supported by a NRSA Fellowship from NIMH (5 F30 MH12575-02).

Keywords

  • Attention
  • Light touch
  • Positron emission tomography (PET)
  • SI
  • SII
  • SIII
  • Somatosensation

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