Photoreceptor-bipolar cell transmission in the perfused retina eyecup of the mudpuppy

Ramon F. Dacheux, Robert F. Miller

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

The hypothesis that a synaptic transmitter is released by photoreceptors in the dark is supported by experiments in which cobalt was used as a synaptic blocking agent, while intracellular recordings of receptors and neurons that are directly post-synaptic to receptors were maintained. In the dark the depolarizing bipolars are hyperpolarized, whereas the hyperpolarizing bipolars are depolarized.

Original languageEnglish (US)
Pages (from-to)963-964
Number of pages2
JournalScience
Volume191
Issue number4230
DOIs
StatePublished - Jan 1 1976

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