Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation

Joshua A. Jackman; Eric Linardy; Daehan Yoo; Jeongeun Seo; Wei Beng Ng; Daniel J. Klemme; Nathan J. Wittenberg; Sang Hyun Oh; Nam Joon Cho

doi:10.1002/smll.201501914

Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation

Joshua A. Jackman, Eric Linardy, Daehan Yoo, Jeongeun Seo, Wei Beng Ng, Daniel J. Klemme, Nathan J. Wittenberg, Sang Hyun Oh, Nam Joon Cho

Electrical and Computer Engineering

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56 Scopus citations

Abstract

A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. Using a materials-selective surface functionalization scheme, passive immobilization of virus-like particles only within the nanoholes is achieved. The findings demonstrate that a low surface coverage of particles only inside the functionalized nanoholes significantly improves nanoplasmonic sensing performance over conventional nanohole arrays.

Original language	English (US)
Pages (from-to)	1159-1166
Number of pages	8
Journal	Small
Volume	12
Issue number	9
DOIs	https://doi.org/10.1002/smll.201501914
State	Published - Mar 2 2016

Bibliographical note

Publisher Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords

biosensing
peptides
plasmonics
sensors, biosensors, nanohole arrays
viruses

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title = "Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation",

abstract = "A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. Using a materials-selective surface functionalization scheme, passive immobilization of virus-like particles only within the nanoholes is achieved. The findings demonstrate that a low surface coverage of particles only inside the functionalized nanoholes significantly improves nanoplasmonic sensing performance over conventional nanohole arrays.",

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AU - Linardy, Eric

AU - Yoo, Daehan

AU - Seo, Jeongeun

AU - Ng, Wei Beng

AU - Klemme, Daniel J.

AU - Wittenberg, Nathan J.

AU - Oh, Sang Hyun

AU - Cho, Nam Joon

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Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation

Abstract

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