Positive and negative exercise test results with and without exercise-induced angina in patients with one healed myocardial infarction: Analysis of baseline variables and long-term prognosis

James N. Karnegis, John P. Matts, Naip Tuna, Kurt Amplatz

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The prognostic implications of exercise test results with and without exerclsed-induced angina are not completely understood. In the Program On the Surgical Control Of the Hyperlipidemias (POSCH), 838 subjects with hyperlipidemia who had one healed myocardial infarction were studied and followed for 6 to 13 years (mean 8.6). Of the 417 control subjects, 279 had a treadmill exercise test result that was definitely positive or negative. Angina was also induced by exercise in 30% ( 45 150) and 8% ( 10 129) of those with a positive and a negative test result, respectively (p < 0.0001). The data showed no difference between subjects with a positive or a negative test result with or without angina as regards levels of blood lipids, type of myocardial infarction (Q or non-Q wave), left ventricular function, or prognosis as defined by death, atheroscierotic coronary heart disease death, or myocardial infarction.

Original languageEnglish (US)
Pages (from-to)701-708
Number of pages8
JournalAmerican Heart Journal
Volume122
Issue number3 PART 1
DOIs
StatePublished - Sep 1991

Bibliographical note

Funding Information:
From the University of Nebraska, and the University of Minnesota. Supported by grant HL 15265 from the National Heart, Lung, and Blood Institute, Bethesda, Md. Received for publication July 23, 1990; accepted March 4, 1991. Reprint requests: James N. Karnegis, MD, PhD, Cardiology Section, VA Medical Center, Omaha, NE 66105. *Program on the Surgical Control of the Hyperlipidemias, 4/1130234

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