Cats receiving PHS were found to have significantly less blood flow to the colon mucosa (51%), submucosa (60%), and muscularis (57%) and to small intestinal mucosa (70%) than control cats. No significant differences were detected in the blood flow to the tissues of the esophagus, stomach, gallbladder, or pancreas. Despite significant increases in blood pressure (147% of control) and pulse (127% of control) cardiac output was not different in the two groups. Tissue blood flows in the control group ranged from the high in the pancreas of 1.36 ± 0.15 ml/g/min followed by the colon, duodenum, jejunum, ileum, and gastric corpus to the low in the gastric antrum of 0.54 ± 0.04 ml/g/min. It is concluded that posterior hypothalamic stimulation can affect tissue blood flow in the gastrointestinal organs but the magnitude of the changes is not sufficient to provide the sole explanation for reported physiologic and pathologic changes associated with such stimuli.
|Original language||English (US)|
|Number of pages||6|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Jun 1973|
Bibliographical noteFunding Information:
Supported by a grant from the John A. Hartford Foundation.