Potential Medical Applications of Fullerenes: An Overview

Seema Thakral, Naveen K Thakral

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

Abstract

Scientists from diverse fields have been intrigued by fullerenes ever since their discovery. The drug-like size, high molecular symmetry, hydrophobicity, and unique electronic configuration of fullerenes renders them potential candidates for investigation as therapeutic agents. The initial difficulty associated with their water-insoluble nature has been successfully eliminated with the use of functionalized fullerenes, without significantly compromising the basic nature of fullerenes. Hence fullerenes are being intensively investigated with respect to their potential anticancer, antiviral, neuroprotectant, and antibacterial activities, as well as the possibility of exploiting them as a carrier for drug and gene delivery. The present overview provides a summary of advancements in the field of biomedical applications of fullerenes.

Original languageEnglish (US)
Title of host publicationBio-Nanotechnology
Subtitle of host publicationA Revolution in Food, Biomedical and Health Sciences
PublisherBlackwell Publishing Ltd
Pages424-441
Number of pages18
ISBN (Print)9780470670378
DOIs
StatePublished - Jan 4 2013

Keywords

  • Anticancer
  • Antiviral
  • Drug delivery
  • Fullerenes
  • Gene delivery
  • Neuroprotectant

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