Abstract
Mammalian decision-making is mediated by the interaction of multiple, neurally and computationally separable decision systems. Having multiple systems requires a mechanism to manage conflict and converge onto the selection of singular actions. A long history of evidence has pointed to the prefrontal cortex as a central component in processing the interactions between distinct decision systems and resolving conflicts among them. In this chapter we review four theories of how that interaction might occur and identify how the medial prefrontal cortex in the rodent may be involved in each theory. We then present experimental predictions implied by the neurobiological data in the context of each theory as a starting point for future investigation of medial prefrontal cortex and decision-making.
Original language | English (US) |
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Title of host publication | What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology |
Editors | Adam T. Brockett, Adam T. Brockett, Linda M. Amarante, Mark Laubach, Matthew R. Roesch, Matthew R. Roesch |
Publisher | Academic Press Inc. |
Pages | 249-281 |
Number of pages | 33 |
ISBN (Print) | 9780323853361 |
DOIs | |
State | Published - Jan 2021 |
Publication series
Name | International Review of Neurobiology |
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Volume | 158 |
ISSN (Print) | 0074-7742 |
ISSN (Electronic) | 2162-5514 |
Bibliographical note
Publisher Copyright:© 2021 Elsevier Inc.
Keywords
- Anterior cingulate cortex
- Central executive
- Decision conflict
- Decision-making
- Deliberation
- Infralimbic cortex
- Multiple decision systems
- Pavlovian
- Prelimbic cortex
- Procedural