TY - JOUR
T1 - Preferential utilization of d-Lactate by Shewanella oneidensis
AU - Brutinel, Evan D.
AU - Gralnick, Jeffrey A.
PY - 2012
Y1 - 2012
N2 - Shewanella oneidensis couples oxidation of lactate to respiration of many substrates. Here we report that llpR (L-lactate-positive regulator, SO_3460) encodes a positive regulator of L-lactate utilization distinct from previously studied regulators. We also demonstrate D-lactate inhibition of L-lactate utilization in S. oneidensis, resulting in preferential utilization of the D isomer.
AB - Shewanella oneidensis couples oxidation of lactate to respiration of many substrates. Here we report that llpR (L-lactate-positive regulator, SO_3460) encodes a positive regulator of L-lactate utilization distinct from previously studied regulators. We also demonstrate D-lactate inhibition of L-lactate utilization in S. oneidensis, resulting in preferential utilization of the D isomer.
UR - http://www.scopus.com/inward/record.url?scp=84870775059&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870775059&partnerID=8YFLogxK
U2 - 10.1128/AEM.02183-12
DO - 10.1128/AEM.02183-12
M3 - Article
C2 - 23001660
AN - SCOPUS:84870775059
SN - 0099-2240
VL - 78
SP - 8474
EP - 8476
JO - Applied and environmental microbiology
JF - Applied and environmental microbiology
IS - 23
ER -