Abstract
A novel approach to the preparation of imidazole-substituted cyclic iodonium salts has been developed via the oxidative cyclization of 1-phenyl-5-iodoimidazole using a cheap and available Oxone/H2SO4 oxidative system. The structure of the new polycyclic heteroarenes has been confirmed by single-crystal X-ray diffractometry, revealing the characteristic structure features for cyclic iodonium salts. The newly produced imidazole-flanked cyclic iodonium compounds were found to readily engage in a heterocyclization reaction with elemental sulfur, affording benzo[5,1-b]imidazothiazoles in good yields.
Original language | English (US) |
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Pages (from-to) | 7163-7178 |
Number of pages | 16 |
Journal | Journal of Organic Chemistry |
Volume | 86 |
Issue number | 10 |
DOIs | |
State | Published - May 21 2021 |
Bibliographical note
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