Prevalence and genetic relatedness of methicillin-susceptible Staphylococcus aureus isolates detected by the Xpert MRSA nasal assay

Sophie S. Arbefeville, Kunyan Zhang, Jennifer S. Kroeger, Wanita J. Howard, Daniel J. Diekema, Sandra S. Richter

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Methicillin-susceptible Staphylococcus aureus (MSSA) isolates lacking mecA yet testing positive on the Xpert MRSA assay were recovered from culture for 7.7% of 248 Xpert-positive nasal samples. These "false-positive" Xpert results may be attributed to staphylococcal cassette chromosome (SCC) elements without the mecA gene. Pulsed-field gel electrophoresis (PFGE) analysis revealed a diverse population of MSSA strains.

Original languageEnglish (US)
Pages (from-to)2996-2999
Number of pages4
JournalJournal of clinical microbiology
Volume49
Issue number8
DOIs
StatePublished - Aug 2011

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