TY - JOUR
T1 - Prevalence and prediction of left atrial thrombus in patients with a recent cerebral ischemic event, who are in sinus rhythm
T2 - A single-center experience
AU - Yahia, Abutaher M.
AU - Shaukat, Aasma
AU - Kirmani, Jawad F.
AU - Latorre, Julius Gene
AU - Qureshi, Adnan I.
PY - 2009/10
Y1 - 2009/10
N2 - BACKGROUND Left atrial thrombus (LAT) is frequently present in patients with cerebral ischemic events (CIE) who are in atrial fibrillation. The prevalence and predictor of LAT in patients who are in sinus rhythm (SR) is unclear. OBJECTIVE To determine the prevalence and identify predictors of LAT formation in patients with CIE who are in SR. METHODS Consecutive patients with CIE who are in SR were evaluated by transesophageal echocardiography (TEE) from July 2000 to August 2001. Patient demographics including cerebrovascular risk factors were recorded. RESULTS LAT was present in 5.5%. Left ventricular systolic dysfunction (LVSD) was present in 25 (10%). Patients' mean age was 59 ± 14 years and 119 (50%) were male. In the univariate analysis, LAT was associated with LVSD (odds ratio [OR] 9.24, 95% confidence interval [CI] 2.8; 10.3) and male patients (OR 4.56, 95% CI: 1.6, 12.6) who had coronary artery disease (OR 3.4, 95% CI: 1.3, 8.4). In the multivariate analysis, LVSD (OR 10.6, CI 2.2-51.6) strongly predicted the development of LAT. CONCLUSIONS LAT is not uncommon in patients CIE, who are in sinus rhythm, especially those with poor left ventricular functions. TEE should be considered in patients with CIE and LVSD for early detection and treatment of LAT.
AB - BACKGROUND Left atrial thrombus (LAT) is frequently present in patients with cerebral ischemic events (CIE) who are in atrial fibrillation. The prevalence and predictor of LAT in patients who are in sinus rhythm (SR) is unclear. OBJECTIVE To determine the prevalence and identify predictors of LAT formation in patients with CIE who are in SR. METHODS Consecutive patients with CIE who are in SR were evaluated by transesophageal echocardiography (TEE) from July 2000 to August 2001. Patient demographics including cerebrovascular risk factors were recorded. RESULTS LAT was present in 5.5%. Left ventricular systolic dysfunction (LVSD) was present in 25 (10%). Patients' mean age was 59 ± 14 years and 119 (50%) were male. In the univariate analysis, LAT was associated with LVSD (odds ratio [OR] 9.24, 95% confidence interval [CI] 2.8; 10.3) and male patients (OR 4.56, 95% CI: 1.6, 12.6) who had coronary artery disease (OR 3.4, 95% CI: 1.3, 8.4). In the multivariate analysis, LVSD (OR 10.6, CI 2.2-51.6) strongly predicted the development of LAT. CONCLUSIONS LAT is not uncommon in patients CIE, who are in sinus rhythm, especially those with poor left ventricular functions. TEE should be considered in patients with CIE and LVSD for early detection and treatment of LAT.
KW - Cerebral ischemic event
KW - Left atrial thrombus
KW - Left ventricular systolic dysfunction
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U2 - 10.1111/j.1552-6569.2009.00371.x
DO - 10.1111/j.1552-6569.2009.00371.x
M3 - Article
C2 - 19490373
AN - SCOPUS:70349524995
SN - 1051-2284
VL - 19
SP - 323
EP - 325
JO - Journal of Neuroimaging
JF - Journal of Neuroimaging
IS - 4
ER -