The objective of this 2-year, double-blind, placebo-controlled, randomized trial involving 48 participants was to determine if biweekly miconazole powder prevents onychomycosis recurrence. Intent-to-treat analysis found no significant differences in mycologic, clinical, or complete onychomycosis reinfection rates or time to reinfection. Limitations include small sample size and dosing regimen.
Bibliographical noteFunding Information:
Funding source: Coloplast Corp, Skin Health Division, through a generous, unrestricted research grant. Dr Warshaw's career has been supported by a VA Cooperative Studies Clinical Research Career Development Grant.