Primary and secondary amenorrhea associated with spironolactone therapy in chronic liver disease

Carol Potter, Dale Willis, Harvey L. Sharp, Sarah Jane Schwarzenberg

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Women with severe liver disease often have amenorrhea that resolves as liver disease abates. We describe three patients with mild to moderate chronic liver disease and amenorrhea. In each case amenorrhea resolved when spironolactone therapy was discontinued. We suggest that spironolactone, an androgen inhibitor, may also cause reversible amenorrhea.

Original languageEnglish (US)
Pages (from-to)141-143
Number of pages3
JournalThe Journal of pediatrics
Volume121
Issue number1
DOIs
StatePublished - Jul 1992

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