Abstract
A 58-year-old white man had dermatomyositis and primary cutaneous B-cell lymphoma. The cutaneous lymphoma was evidenced by a noduloulcerative disease of the lower extremities. Histologic results resembled a T-cell process with a diffuse, superficial infiltrate composed of small- and medium-sized lymphocytes with angioinvasion and epidermotropism. The infiltrate extended into the deep dermis and panniculus with scattered large lymphocytes and necrosis. With the help of gene-rearrangement analysis and immunophenotyping, the true B-cell lineage was discovered. The importance of gene-rearrangement analysis and immunophenotyping in the diagnosis of cutaneous lymphoma is emphasized.
Original language | English (US) |
---|---|
Pages (from-to) | 288-292 |
Number of pages | 5 |
Journal | Journal of the American Academy of Dermatology |
Volume | 26 |
Issue number | 2 |
DOIs | |
State | Published - Jan 1 1992 |
Externally published | Yes |