Primary Infection with Zidovudine-Resistant HIV

P. Hermans; S. Sprecher; N. Clumeck; Bernard Masquelier; Emmanuelle Lemoigne; Isabelle Pellegrin; Danielle Douard; Boris Sandler; Herve J.a. Fleury; Alejo Erice; Henry H. Balfour

doi:10.1056/NEJM199310073291514

Primary Infection with Zidovudine-Resistant HIV

P. Hermans, S. Sprecher, N. Clumeck, Bernard Masquelier, Emmanuelle Lemoigne, Isabelle Pellegrin, Danielle Douard, Boris Sandler, Herve J.a. Fleury, Alejo Erice, Henry H. Balfour

Laboratory Medicine and Pathology

Research output: Contribution to journal › Letter › peer-review

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Abstract

To the Editor: Erice et al. (April 22 issue)¹ described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991. We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene – those associated with reduced sensitivity to zidovudine and didanosine, respectively. We…

Original language	English (US)
Pages (from-to)	1123-1124
Number of pages	2
Journal	New England Journal of Medicine
Volume	329
Issue number	15
DOIs	https://doi.org/10.1056/NEJM199310073291514
State	Published - Oct 7 1993

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title = "Primary Infection with Zidovudine-Resistant HIV",

abstract = "To the Editor: Erice et al. (April 22 issue)1 described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991. We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene – those associated with reduced sensitivity to zidovudine and didanosine, respectively. We…",

author = "P. Hermans and S. Sprecher and N. Clumeck and Bernard Masquelier and Emmanuelle Lemoigne and Isabelle Pellegrin and Danielle Douard and Boris Sandler and Fleury, {Herve J.a.} and Alejo Erice and Balfour, {Henry H.}",

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T1 - Primary Infection with Zidovudine-Resistant HIV

AU - Hermans, P.

AU - Sprecher, S.

AU - Clumeck, N.

AU - Masquelier, Bernard

AU - Lemoigne, Emmanuelle

AU - Pellegrin, Isabelle

AU - Douard, Danielle

AU - Sandler, Boris

AU - Fleury, Herve J.a.

AU - Erice, Alejo

AU - Balfour, Henry H.

PY - 1993/10/7

Y1 - 1993/10/7

N2 - To the Editor: Erice et al. (April 22 issue)1 described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991. We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene – those associated with reduced sensitivity to zidovudine and didanosine, respectively. We…

AB - To the Editor: Erice et al. (April 22 issue)1 described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991. We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene – those associated with reduced sensitivity to zidovudine and didanosine, respectively. We…

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JO - New England Journal of Medicine

JF - New England Journal of Medicine

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ER -

Primary Infection with Zidovudine-Resistant HIV

Abstract

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