Abstract
The object of toxicokinetics is the investigation of absorption, distribution, and elimination of toxicants and their toxicologically relevant metabolites as functions of dose and time.
Original language | English (US) |
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Title of host publication | Toxicology and Risk Assessment |
Subtitle of host publication | A Comprehensive Introduction |
Publisher | John Wiley & Sons, Ltd |
Pages | 19-203 |
Number of pages | 185 |
ISBN (Print) | 9780470868935 |
DOIs | |
State | Published - Feb 8 2008 |
Keywords
- Anion-transport systems
- Cancer-linked disease
- Enzyme-mediated substance conversion
- Intravascular thrombus formation
- Isoenzymes exhibiting different substrate specificities
- Messenger ribonucleic acid (mRNA)
- Morphologically and functionally differing entities
- One-compartment model saturation kinetics
- Richly perfused organs
- Toxic potential and (estimated) exposure