Abstract
Carr-Purcell and Hahn spin-echo (SE) measurements were used to estimate the apparent transverse relaxation time constant (T2+) of water and metabolites in human brain at 4T and 7T. A significant reduction in the T2+ values of proton resonances (water, N-acetylaspartate, and creatine/phosphocreatine) was observed with increasing magnetic field strength and was attributed mainly to increased dynamic dephasing due to increased local susceptibility gradients. At high field, signal loss resulting from T2+ decay can be substantially reduced using a Carr-Purcell-type SE sequence.
Original language | English (US) |
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Pages (from-to) | 629-633 |
Number of pages | 5 |
Journal | Magnetic resonance in medicine |
Volume | 47 |
Issue number | 4 |
DOIs | |
State | Published - 2002 |
Keywords
- Adiabatic pulse
- Carr-Purcell spin echo
- Cerebral metabolites
- High magnetic field
- T relaxation time