P1-antigen-containing avian egg whites as inhibitors of P adhesins among wild-type Escherichia coli strains from patients with urosepsis

J. R. Johnson, A. E. Ross

Research output: Contribution to journalComment/debatepeer-review

14 Scopus citations

Abstract

Among 58 Escherichia coli urosepsis isolates, P1-antigen-containing dove and pigeon egg whites were significantly more effective inhibitors of P- adhesin-specific agglutination than were chicken egg whites or globoside. Globoside's inefficacy may have resulted from a proadherence effect of globoside's lipid tail. Adhesin phenotypes determined with dove and pigeon egg whites as agglutination inhibitors corresponded closely with phenotypes defined by comparative hemagglutination of human P1 and p erythrocytes. These data suggest that avian P1-antigen-containing substances may provide a useful alternative method for P adhesin inhibition among uropathogenic E. coli strains.

Original languageEnglish (US)
Pages (from-to)4902-4905
Number of pages4
JournalInfection and immunity
Volume61
Issue number11
DOIs
StatePublished - 1993

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