Qualitative and quantitative characterization of mutagens in commercial beef extract

Robert J. Turesky; John S. Wishnok; Steven R. Tannenbaum; Rolland A. Pfund; George H. Buchi

doi:10.1093/carcin/4.7.863

Qualitative and quantitative characterization of mutagens in commercial beef extract

Robert J. Turesky, John S. Wishnok, Steven R. Tannenbaum, Rolland A. Pfund, George H. Buchi

Medicinal Chemistry

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Abstract

Two mutagenic compounds have been isolated and purified from commercial beef extract. These two compounds have chemical, chromatographic, spectroscopic and biological behavior indistinguishable from those of the two known mutagens 2-amino-3-methyl-imidazo-[4,5-f]-quinoline and 2-amino-3,8-dimethyl-imidazo-[4,5-f]-quinoxaline.

Original language	English (US)
Pages (from-to)	863-866
Number of pages	4
Journal	Carcinogenesis
Volume	4
Issue number	7
DOIs	https://doi.org/10.1093/carcin/4.7.863
State	Published - 1983

Bibliographical note

Funding Information:
This investigation was supported by PHS Grant Number 5-P01-CA26731-03, awarded by the National Cancer Institute, DHHS.

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title = "Qualitative and quantitative characterization of mutagens in commercial beef extract",

abstract = "Two mutagenic compounds have been isolated and purified from commercial beef extract. These two compounds have chemical, chromatographic, spectroscopic and biological behavior indistinguishable from those of the two known mutagens 2-amino-3-methyl-imidazo-[4,5-f]-quinoline and 2-amino-3,8-dimethyl-imidazo-[4,5-f]-quinoxaline.",

author = "Turesky, {Robert J.} and Wishnok, {John S.} and Tannenbaum, {Steven R.} and Pfund, {Rolland A.} and Buchi, {George H.}",

note = "Funding Information: This investigation was supported by PHS Grant Number 5-P01-CA26731-03, awarded by the National Cancer Institute, DHHS.",

year = "1983",

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language = "English (US)",

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AU - Turesky, Robert J.

AU - Wishnok, John S.

AU - Tannenbaum, Steven R.

AU - Pfund, Rolland A.

AU - Buchi, George H.

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PY - 1983

Y1 - 1983

N2 - Two mutagenic compounds have been isolated and purified from commercial beef extract. These two compounds have chemical, chromatographic, spectroscopic and biological behavior indistinguishable from those of the two known mutagens 2-amino-3-methyl-imidazo-[4,5-f]-quinoline and 2-amino-3,8-dimethyl-imidazo-[4,5-f]-quinoxaline.

AB - Two mutagenic compounds have been isolated and purified from commercial beef extract. These two compounds have chemical, chromatographic, spectroscopic and biological behavior indistinguishable from those of the two known mutagens 2-amino-3-methyl-imidazo-[4,5-f]-quinoline and 2-amino-3,8-dimethyl-imidazo-[4,5-f]-quinoxaline.

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Qualitative and quantitative characterization of mutagens in commercial beef extract

Abstract

Bibliographical note

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