Rac-(6S)-6-Hydroxy-6-{2-[2-(propan-2-ylidene)hydrazinylidene]propyl} indolo[2,1-b]quinazolin-12(6H)-one

Matthew E. Rodstein, Paul D. Steffen, Bogdana Krivogorsky, Peter Grundt

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Thechiraltitlecompound,C 21H 20N 4O 2, crystallizes as a racemic mixture. In the crystal, molecules form centrosymmetric π-overlapping dimers [inter-planar distance = 3.338 (6) Å], which are further connected along the a axis forming centrosymmetric dimers via O-H⋯N hydrogen bonds. C-H⋯O interactions are also observed. The indolo[2,1-b]quinazoline group is somewhat bent, with a small dihedral angle of 6.3 (4)° between the plane of the quinazoline system and the plane of the benzene ring of the indole moiety. The C=N-N=C atoms of the azine group is oriented almost perpendicular [84.1 (2)°] to the mean plane of the quinazoline system.

Original languageEnglish (US)
Pages (from-to)o2695-o2696
JournalActa Crystallographica Section E: Structure Reports Online
Volume67
Issue number10
DOIs
StatePublished - Oct 2011

Keywords

  • R factor = 0.062
  • T = 100 K
  • mean σ(C-C) = 0.006 Å
  • single-crystal X-ray study
  • wR factor = 0.161; data-to-parameter ratio = 11.9

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