Radiation-associated breast cancer and gonadal hormone exposure: A report from the Childhood Cancer Survivor Study

Chaya S. Moskowitz, Joanne F. Chou, Charles A. Sklar, Dana Barnea, Cécile M. Ronckers, Danielle Novetsky Friedman, Joseph P. Neglia, Lucie Turcotte, Rebecca M. Howell, Tara O. Henderson, Gregory T. Armstrong, Wendy M. Leisenring, Leslie L. Robison, Flora E. Van Leeuwen, Malcolm C. Pike, Kevin C. Oeffinger

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Background:The relationship between hormone exposure and breast cancer risk in women treated with chest radiotherapy for childhood cancer is uncertain.Methods:Participants included 1108 females from the Childhood Cancer Survivor Study who were diagnosed with childhood cancer 1970-1986, treated with chest radiotherapy, and survived to ages

Original languageEnglish (US)
Pages (from-to)290-299
Number of pages10
JournalBritish Journal of Cancer
Volume117
Issue number2
DOIs
StatePublished - Jul 11 2017

Bibliographical note

Publisher Copyright:
© 2017 Cancer Research UK. All rights reserved.

Keywords

  • hormone replacement therapy
  • late effects
  • pediatric malignancy
  • second malignancies
  • supradiaphragmatic radiotherapy

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