Rapid dynamic CT scanning to distinguish schizophrenic from normal subjects

Maurice Dysken; Clifford S. Patlak; Glen D. Dobben; Karen D. Pettigrew; John J. Bartko; Elizabeth M. Burns; John Davis; Darrel A. Regier

doi:10.1016/0165-1781(87)90008-4

Rapid dynamic CT scanning to distinguish schizophrenic from normal subjects

Maurice Dysken, Clifford S. Patlak, Glen D. Dobben, Karen D. Pettigrew, John J. Bartko, Elizabeth M. Burns, John Davis, Darrel A. Regier

Psychiatry & Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Rapid dynamic computerized axial tomography (CT) density-time curves were used to detect abnormal brain regions in groups of controls and DSM-III diagnosed schizophrenics. Density-time curves were designated as plateau curves if, following a bolus injection of contrast material, they exhibited a plateau from the peak value rather than a decrease. Five of the 10 schizophrenics versus none of the 11 controls were found to possess two or more plateau curves. The psysiological basis for the plateau curves is not known, but an increase in blood-brain-barrier permeability could be involved.

Original language	English (US)
Pages (from-to)	165-175
Number of pages	11
Journal	Psychiatry Research
Volume	20
Issue number	2
DOIs	https://doi.org/10.1016/0165-1781(87)90008-4
State	Published - Feb 1987

Keywords

Schizophrenia
dynamic computed tomography
plateau regions

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title = "Rapid dynamic CT scanning to distinguish schizophrenic from normal subjects",

abstract = "Rapid dynamic computerized axial tomography (CT) density-time curves were used to detect abnormal brain regions in groups of controls and DSM-III diagnosed schizophrenics. Density-time curves were designated as plateau curves if, following a bolus injection of contrast material, they exhibited a plateau from the peak value rather than a decrease. Five of the 10 schizophrenics versus none of the 11 controls were found to possess two or more plateau curves. The psysiological basis for the plateau curves is not known, but an increase in blood-brain-barrier permeability could be involved.",

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author = "Maurice Dysken and Patlak, {Clifford S.} and Dobben, {Glen D.} and Pettigrew, {Karen D.} and Bartko, {John J.} and Burns, {Elizabeth M.} and John Davis and Regier, {Darrel A.}",

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AU - Dysken, Maurice

AU - Patlak, Clifford S.

AU - Dobben, Glen D.

AU - Pettigrew, Karen D.

AU - Bartko, John J.

AU - Burns, Elizabeth M.

AU - Davis, John

AU - Regier, Darrel A.

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N2 - Rapid dynamic computerized axial tomography (CT) density-time curves were used to detect abnormal brain regions in groups of controls and DSM-III diagnosed schizophrenics. Density-time curves were designated as plateau curves if, following a bolus injection of contrast material, they exhibited a plateau from the peak value rather than a decrease. Five of the 10 schizophrenics versus none of the 11 controls were found to possess two or more plateau curves. The psysiological basis for the plateau curves is not known, but an increase in blood-brain-barrier permeability could be involved.

AB - Rapid dynamic computerized axial tomography (CT) density-time curves were used to detect abnormal brain regions in groups of controls and DSM-III diagnosed schizophrenics. Density-time curves were designated as plateau curves if, following a bolus injection of contrast material, they exhibited a plateau from the peak value rather than a decrease. Five of the 10 schizophrenics versus none of the 11 controls were found to possess two or more plateau curves. The psysiological basis for the plateau curves is not known, but an increase in blood-brain-barrier permeability could be involved.

KW - Schizophrenia

KW - dynamic computed tomography

KW - plateau regions

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Rapid dynamic CT scanning to distinguish schizophrenic from normal subjects

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