Rapid quantitation of protein levels by combining microfluidics and printed electronic transducers

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report a method to quantify protein levels using a combination of printed electronic and microfluidic technologies. The label-free method transduces the binding of ricin to nucleic acid aptamers into an amplified potentiometric signal. Microfluidic channels physically separate the active sensor surface from the EGT-transducer, permitting the capture of ricin in orange juice and milk. Under flow, signals arise between 1-45 minutes without any pre-processing or rinsing steps. Easy fabrication, multiplexing, and operation, combined with rapid quantitation, make our device promising for parallelized monitoring of toxin levels in food and other environmental samples.

Original languageEnglish (US)
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages1262-1263
Number of pages2
ISBN (Electronic)9780979806490
StatePublished - Jan 1 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: Oct 9 2016Oct 13 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period10/9/1610/13/16

Keywords

  • Biosensor
  • Electrochemical
  • Printed electronics
  • Transistor

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