TY - JOUR
T1 - Rational design of all-solid-state ion-selective electrodes and reference electrodes
AU - Hu, Jinbo
AU - Stein, Andreas
AU - Bühlmann, Philippe
N1 - Publisher Copyright:
© 2015 Elsevier B.V.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Potentiometric sensing, which requires the use of ion-selective electrodes (ISEs) and reference electrodes, is used to determine electrochemically the concentration of target ions in a variety of chemical environments. In view of the need for more affordable and portable analytical devices with small sample volumes, all-solid-state ISEs and reference electrodes, in which a solid contact is used as ion-to-electron transducer, are highly desirable. This review describes how all-solid-state ISEs and reference electrodes function and presents important aspects that should be considered when designing such sensors for specific applications. Approaches to improving reproducibility, the stability of the emf response, lowering detection limits, and novel sensor designs are discussed along with specific examples from the recent literature. Emphasis is placed on the ion-to-electron transduction mechanism and the development of new solid contact materials, with a particular view to miniaturized ion-sensing devices with low cost and calibration-free sensing.
AB - Potentiometric sensing, which requires the use of ion-selective electrodes (ISEs) and reference electrodes, is used to determine electrochemically the concentration of target ions in a variety of chemical environments. In view of the need for more affordable and portable analytical devices with small sample volumes, all-solid-state ISEs and reference electrodes, in which a solid contact is used as ion-to-electron transducer, are highly desirable. This review describes how all-solid-state ISEs and reference electrodes function and presents important aspects that should be considered when designing such sensors for specific applications. Approaches to improving reproducibility, the stability of the emf response, lowering detection limits, and novel sensor designs are discussed along with specific examples from the recent literature. Emphasis is placed on the ion-to-electron transduction mechanism and the development of new solid contact materials, with a particular view to miniaturized ion-sensing devices with low cost and calibration-free sensing.
KW - Calibration-free sensor
KW - Ion sensing
KW - Ion-selective electrode
KW - Ion-to-electron transduction
KW - Reference electrode
KW - Sensor miniaturization
KW - Solid contact
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U2 - 10.1016/j.trac.2015.11.004
DO - 10.1016/j.trac.2015.11.004
M3 - Review article
AN - SCOPUS:84950997910
SN - 0165-9936
VL - 76
SP - 102
EP - 114
JO - TrAC - Trends in Analytical Chemistry
JF - TrAC - Trends in Analytical Chemistry
ER -