Renal Ischemia and Functional Outcomes Following Partial Nephrectomy

Joseph R. Zabell; Jitao Wu; Chalairat Suk-Ouichai; Steven C. Campbell

doi:10.1016/j.ucl.2016.12.010

Renal Ischemia and Functional Outcomes Following Partial Nephrectomy

Joseph R. Zabell, Jitao Wu, Chalairat Suk-Ouichai, Steven C. Campbell

Urology

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

Renal function after renal cancer surgery is a critical component of survivorship. Quantity and quality of preserved parenchyma are the most important determinants of functional recovery; type and duration of ischemia play secondary roles. Several studies evaluated surgical techniques to minimize ischemia; however, long-term outcomes and potential benefits over clamped partial nephrectomy (PN) have not been consistently demonstrated. Analysis of acute kidney injury (AKI) after PN suggest that most kidneys recover strongly even if AKI is experienced after surgery. Ongoing study is required to evaluate long-term implications of AKI after PN and further assess impact of ischemia on functional outcomes.

Original language	English (US)
Pages (from-to)	243-255
Number of pages	13
Journal	Urologic Clinics of North America
Volume	44
Issue number	2
DOIs	https://doi.org/10.1016/j.ucl.2016.12.010
State	Published - May 2017

Keywords

Functional recovery
Ischemia
Partial nephrectomy
Radical nephrectomy
Renal cell carcinoma

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.1016/j.ucl.2016.12.010

OpenUrl availability

Full text

Cite this

@article{1aaa7b36d1ab4e0cb397544eb5200a5a,

title = "Renal Ischemia and Functional Outcomes Following Partial Nephrectomy",

abstract = "Renal function after renal cancer surgery is a critical component of survivorship. Quantity and quality of preserved parenchyma are the most important determinants of functional recovery; type and duration of ischemia play secondary roles. Several studies evaluated surgical techniques to minimize ischemia; however, long-term outcomes and potential benefits over clamped partial nephrectomy (PN) have not been consistently demonstrated. Analysis of acute kidney injury (AKI) after PN suggest that most kidneys recover strongly even if AKI is experienced after surgery. Ongoing study is required to evaluate long-term implications of AKI after PN and further assess impact of ischemia on functional outcomes.",

keywords = "Functional recovery, Ischemia, Partial nephrectomy, Radical nephrectomy, Renal cell carcinoma",

author = "Zabell, {Joseph R.} and Jitao Wu and Chalairat Suk-Ouichai and Campbell, {Steven C.}",

year = "2017",

month = may,

doi = "10.1016/j.ucl.2016.12.010",

language = "English (US)",

volume = "44",

pages = "243--255",

journal = "Urologic Clinics of North America",

issn = "0094-0143",

publisher = "W.B. Saunders Ltd",

number = "2",

}

TY - JOUR

T1 - Renal Ischemia and Functional Outcomes Following Partial Nephrectomy

AU - Zabell, Joseph R.

AU - Wu, Jitao

AU - Suk-Ouichai, Chalairat

AU - Campbell, Steven C.

PY - 2017/5

Y1 - 2017/5

N2 - Renal function after renal cancer surgery is a critical component of survivorship. Quantity and quality of preserved parenchyma are the most important determinants of functional recovery; type and duration of ischemia play secondary roles. Several studies evaluated surgical techniques to minimize ischemia; however, long-term outcomes and potential benefits over clamped partial nephrectomy (PN) have not been consistently demonstrated. Analysis of acute kidney injury (AKI) after PN suggest that most kidneys recover strongly even if AKI is experienced after surgery. Ongoing study is required to evaluate long-term implications of AKI after PN and further assess impact of ischemia on functional outcomes.

AB - Renal function after renal cancer surgery is a critical component of survivorship. Quantity and quality of preserved parenchyma are the most important determinants of functional recovery; type and duration of ischemia play secondary roles. Several studies evaluated surgical techniques to minimize ischemia; however, long-term outcomes and potential benefits over clamped partial nephrectomy (PN) have not been consistently demonstrated. Analysis of acute kidney injury (AKI) after PN suggest that most kidneys recover strongly even if AKI is experienced after surgery. Ongoing study is required to evaluate long-term implications of AKI after PN and further assess impact of ischemia on functional outcomes.

KW - Functional recovery

KW - Ischemia

KW - Partial nephrectomy

KW - Radical nephrectomy

KW - Renal cell carcinoma

UR - http://www.scopus.com/inward/record.url?scp=85017466190&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85017466190&partnerID=8YFLogxK

U2 - 10.1016/j.ucl.2016.12.010

DO - 10.1016/j.ucl.2016.12.010

M3 - Review article

C2 - 28411916

AN - SCOPUS:85017466190

SN - 0094-0143

VL - 44

SP - 243

EP - 255

JO - Urologic Clinics of North America

JF - Urologic Clinics of North America

IS - 2

ER -

Renal Ischemia and Functional Outcomes Following Partial Nephrectomy

Abstract

Keywords

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this