Reproduction and transplantation: Report on the AST Consensus Conference on Reproductive Issues and Transplantation

Dianne B. McKay, Michelle A. Josephson, Vincent T. Armenti, Phyllis August, Lisa A. Coscia, Connie L. Davis, John M. Davison, Thomas Easterling, Jan M. Friedman, Susan Hou, Janet Karlix, Kathleen D. Lake, Marshall Lindheimer, Arthur J. Matas, Michael J. Moritz, Caroline A. Riely, Lainie Friedman Ross, James R. Scott, Lynne E. Wagoner, Lucile WrenshallPatricia L. Adams, Ginny L. Bumgardner, Richard N. Fine, Simin Goral, Sheri M. Krams, Olivia M. Martinez, Nina Tolkoff-Rubin, Martha Pavlakis, Velma Scantlebury

Research output: Contribution to journalArticlepeer-review

275 Scopus citations


It has been almost 50 years since the first child was born to a female transplant recipient. Since that time pregnancy has become common after transplantation, but physicians have been left to rely on case reports, small series and data from voluntary registries to guide the care of their patients. Many uncertainties exist including the risks that pregnancy presents to the graft, the patient herself, and the long-term risks to the fetus. It is also unclear how to best modify immunosuppressive agents or treat rejection during pregnancy, especially in light of newer agents available where pregnancy safety has not been established. To begin to address uncertainties and define clinical practice guidelines for the transplant physician and obstetrical caregivers, a consensus conference was held in Bethesda, Md. The conferees summarized both what is known and important gaps in our knowledge. They also identified key areas of agreement, and posed a number of critical questions, the resolution of which is necessary in order to establish evidence-based guidelines. The manuscript summarizes the deliberations and conclusions of the conference as well as specific recommendations based on current knowledge in the field.

Original languageEnglish (US)
Pages (from-to)1592-1599
Number of pages8
JournalAmerican Journal of Transplantation
Issue number7
StatePublished - Jul 2005


  • Fetus
  • Outcomes
  • Pregnancy
  • Transplantation

Fingerprint Dive into the research topics of 'Reproduction and transplantation: Report on the AST Consensus Conference on Reproductive Issues and Transplantation'. Together they form a unique fingerprint.

Cite this