Resolution of Superficial Necrolytic Dermatitis Following Excision of a Glucagon-Secreting Pancreatic Neoplasm in a Dog

Sheila M.F. Torres, Dennis D. Caywood, Timothy D. O'Brien, Terrance P. O'Leary, Patrick J. McKeever

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

An 11-year-old, neutered male standard poodle was diagnosed with superficial necrolytic dermatitis and a glucagon-secreting pancreatic islet neoplasm based on clinical, biochemical, histopathological, immunohistochemical, and hormonal findings. Hyperglucagonemia, hyperinsulinemia, and hypoaminoacidemia were observed on preoperative laboratory analysis. Abnormal laboratory values returned to normal, and complete resolution of skin lesions occurred after tumor excision. The dog has remained clinically normal for six months following surgery.

Original languageEnglish (US)
Pages (from-to)313-319
Number of pages7
JournalJournal of the American Animal Hospital Association
Volume33
Issue number4
DOIs
StatePublished - 1997

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