Retinal Nerve Fibre Layer Thickness Increases with Decreasing Spectralis OCT Signal Strength in Normal Eyes

Margaret R. Strampe; Luai T Eldweik; Benjamin C. Chaon; Sarah Maki; Tyler Wieland; Celine Satija; Collin McClelland; Michael S. Lee

doi:10.1080/01658107.2019.1653934

Retinal Nerve Fibre Layer Thickness Increases with Decreasing Spectralis OCT Signal Strength in Normal Eyes

Margaret R. Strampe, Luai T Eldweik, Benjamin C. Chaon, Sarah Maki, Tyler Wieland, Celine Satija, Collin McClelland, Michael S. Lee

Ophthalmology & Visual Neurosciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We sought to determine effect of signal strength on mean retinal nerve fibre layer (RNFL) using Spectralis optical coherence tomography (S-OCT). Thirty normal subjects (18 female, mean 37.9 years, range 24-61) were imaged with S-OCT using variably dense Bangerter foils to alter Q value (1 unit signal strength = 4 units Q). We found a statistically significant (p < 0.01) linear relationship (R = 0.8643) between Q and RNFL (1 unit decrease Q = 0.181 um mean RNFL increase). Unlike previous observations of Cirrus and Stratus OCT, we found RNFL thickness does not decrease with decreasing signal strength in S-OCT.

Original language	English (US)
Pages (from-to)	100-103
Number of pages	4
Journal	Neuro-Ophthalmology
Volume	44
Issue number	2
DOIs	https://doi.org/10.1080/01658107.2019.1653934
State	Published - Mar 3 2020

Bibliographical note

Publisher Copyright:
© 2019, © 2019 Taylor & Francis Group, LLC.

Keywords

OCT
RNFL
Retinal nerve fiber layer
Spectralis
optical coherence tomography
signal strength

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title = "Retinal Nerve Fibre Layer Thickness Increases with Decreasing Spectralis OCT Signal Strength in Normal Eyes",

abstract = "We sought to determine effect of signal strength on mean retinal nerve fibre layer (RNFL) using Spectralis optical coherence tomography (S-OCT). Thirty normal subjects (18 female, mean 37.9 years, range 24-61) were imaged with S-OCT using variably dense Bangerter foils to alter Q value (1 unit signal strength = 4 units Q). We found a statistically significant (p < 0.01) linear relationship (R = 0.8643) between Q and RNFL (1 unit decrease Q = 0.181 um mean RNFL increase). Unlike previous observations of Cirrus and Stratus OCT, we found RNFL thickness does not decrease with decreasing signal strength in S-OCT.",

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AU - Maki, Sarah

AU - Wieland, Tyler

AU - Satija, Celine

AU - McClelland, Collin

AU - Lee, Michael S.

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Retinal Nerve Fibre Layer Thickness Increases with Decreasing Spectralis OCT Signal Strength in Normal Eyes

Abstract

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Keywords

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