Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine

Li-Na Wei; Chih Hao Lee; Liming Chang

doi:10.1016/0303-7207(95)03570-W

Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine

Li-Na Wei, Chih Hao Lee, Liming Chang

Pharmacology

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Cellular retinoic acid-binding protein-I (CRABP-I) gene expression is induced in mouse embryonal carcinoma P19 cells specifically by retinoic acid (RA) and the induction is enhanced by sphinganine. The effects of retinoic acid and sphinganine on CRABP-I gene expression can be accounted for by a stimulation of its transcription rate. Using a lacZ reporter system, it was determined that a DNA fragment containing a putative AP-1 binding site in the promoter region of CRABP-I gene is required for the up-regulation of CRABP-I gene transcription.

Original language	English (US)
Pages (from-to)	207-211
Number of pages	5
Journal	Molecular and Cellular Endocrinology
Volume	111
Issue number	2
DOIs	https://doi.org/10.1016/0303-7207(95)03570-W
State	Published - Jun 1995

Bibliographical note

Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.

Keywords

AP-1
Cellular retinoic acid-binding protein-I
Gene regulation
Sphinganine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.1016/0303-7207(95)03570-W

OpenUrl availability

Full text

Cite this

@article{c24db886f0b04c67b5cb232aeea1a22b,

title = "Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine",

abstract = "Cellular retinoic acid-binding protein-I (CRABP-I) gene expression is induced in mouse embryonal carcinoma P19 cells specifically by retinoic acid (RA) and the induction is enhanced by sphinganine. The effects of retinoic acid and sphinganine on CRABP-I gene expression can be accounted for by a stimulation of its transcription rate. Using a lacZ reporter system, it was determined that a DNA fragment containing a putative AP-1 binding site in the promoter region of CRABP-I gene is required for the up-regulation of CRABP-I gene transcription.",

keywords = "AP-1, Cellular retinoic acid-binding protein-I, Gene regulation, Sphinganine",

author = "Li-Na Wei and Lee, {Chih Hao} and Liming Chang",

year = "1995",

month = jun,

doi = "10.1016/0303-7207(95)03570-W",

language = "English (US)",

volume = "111",

pages = "207--211",

journal = "Molecular and Cellular Endocrinology",

issn = "0303-7207",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine

AU - Wei, Li-Na

AU - Lee, Chih Hao

AU - Chang, Liming

PY - 1995/6

Y1 - 1995/6

N2 - Cellular retinoic acid-binding protein-I (CRABP-I) gene expression is induced in mouse embryonal carcinoma P19 cells specifically by retinoic acid (RA) and the induction is enhanced by sphinganine. The effects of retinoic acid and sphinganine on CRABP-I gene expression can be accounted for by a stimulation of its transcription rate. Using a lacZ reporter system, it was determined that a DNA fragment containing a putative AP-1 binding site in the promoter region of CRABP-I gene is required for the up-regulation of CRABP-I gene transcription.

AB - Cellular retinoic acid-binding protein-I (CRABP-I) gene expression is induced in mouse embryonal carcinoma P19 cells specifically by retinoic acid (RA) and the induction is enhanced by sphinganine. The effects of retinoic acid and sphinganine on CRABP-I gene expression can be accounted for by a stimulation of its transcription rate. Using a lacZ reporter system, it was determined that a DNA fragment containing a putative AP-1 binding site in the promoter region of CRABP-I gene is required for the up-regulation of CRABP-I gene transcription.

KW - AP-1

KW - Cellular retinoic acid-binding protein-I

KW - Gene regulation

KW - Sphinganine

UR - http://www.scopus.com/inward/record.url?scp=0029002113&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029002113&partnerID=8YFLogxK

U2 - 10.1016/0303-7207(95)03570-W

DO - 10.1016/0303-7207(95)03570-W

M3 - Article

C2 - 7556883

AN - SCOPUS:0029002113

SN - 0303-7207

VL - 111

SP - 207

EP - 211

JO - Molecular and Cellular Endocrinology

JF - Molecular and Cellular Endocrinology

IS - 2

ER -

Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine

Abstract

Bibliographical note

Keywords

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this