Review article: Lack of clinical significance of the interaction between H2‐receptor antagonists and ethanol

M. D. LEVITT

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations

Abstract

It has been proposed that an appreciable fraction of ingested ethanol is metabolized in the gastric mucosa and that inhibition of this metabolism by H2‐receptor antagonists produces clinically important increases in blood ethanol. This paper reviews available data concerning gastric metabolism of ethanol and the influence of H2‐antagonists on ethanol metabolism. It concludes that very little, if any, metabolism of ethanol is likely to occur in the gastric mucosa, and the interaction between H2‐antagonists and ethanol is clinically insignificant.

Original languageEnglish (US)
Pages (from-to)131-138
Number of pages8
JournalAlimentary Pharmacology & Therapeutics
Volume7
Issue number2
DOIs
StatePublished - Apr 1993

Fingerprint

Dive into the research topics of 'Review article: Lack of clinical significance of the interaction between H<sub>2</sub>‐receptor antagonists and ethanol'. Together they form a unique fingerprint.

Cite this