Revisiting Trypanosome Mitochondrial Genome Mysteries: Broader and Deeper

Sara L. Zimmer

doi:10.1016/j.pt.2018.09.006

Revisiting Trypanosome Mitochondrial Genome Mysteries: Broader and Deeper

Sara L. Zimmer

Biomedical Sciences

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

What do the products of a genome do, and when and why are they needed? For the protein products of the trypanosomatid parasites’ mitochondrial genomes, the total expressed protein repertoire and the identities of the more difficult-to-characterize products have been challenging to acquire. Comparative genomics and new technologies may resolve that.

Original language	English (US)
Pages (from-to)	102-104
Number of pages	3
Journal	Trends in Parasitology
Volume	35
Issue number	2
DOIs	https://doi.org/10.1016/j.pt.2018.09.006
State	Published - Feb 2019

Keywords

NADH dehydrogenase
RNA editing
electron transport chain
kinetoplastid
maxicircle
mitochondrial ribosome

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abstract = "What do the products of a genome do, and when and why are they needed? For the protein products of the trypanosomatid parasites{\textquoteright} mitochondrial genomes, the total expressed protein repertoire and the identities of the more difficult-to-characterize products have been challenging to acquire. Comparative genomics and new technologies may resolve that.",

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KW - NADH dehydrogenase

KW - RNA editing

KW - electron transport chain

KW - kinetoplastid

KW - maxicircle

KW - mitochondrial ribosome

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Revisiting Trypanosome Mitochondrial Genome Mysteries: Broader and Deeper

Abstract

Keywords

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