Ring of Power: A Band of Peptidergic Midbrain Neurons that Binds Motivation

Anne L. Collins; A. R. Wolff; Benjamin T. Saunders

doi:10.1016/j.neuron.2019.07.022

Ring of Power: A Band of Peptidergic Midbrain Neurons that Binds Motivation

Anne L. Collins, A. R. Wolff, Benjamin T. Saunders

Neuroscience

Research output: Contribution to journal › Short survey › peer-review

Abstract

A recent Cell paper identifies a novel population of neurons within the ventral tegmental area producing the endogenous opioid nociceptin that regulates dopamine neuron firing and acts uniquely to gate motivation in reward seeking. These results highlight neuropeptidergic signaling as a critical component of functional heterogeneity in the midbrain.

Original language	English (US)
Pages (from-to)	364-366
Number of pages	3
Journal	Neuron
Volume	103
Issue number	3
DOIs	https://doi.org/10.1016/j.neuron.2019.07.022
State	Published - Aug 7 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc.

Keywords

dopamine
fiber photometry
nociceptin
opioids
reward
ventral tegmental area

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10.1016/j.neuron.2019.07.022

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abstract = "A recent Cell paper identifies a novel population of neurons within the ventral tegmental area producing the endogenous opioid nociceptin that regulates dopamine neuron firing and acts uniquely to gate motivation in reward seeking. These results highlight neuropeptidergic signaling as a critical component of functional heterogeneity in the midbrain.",

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KW - reward

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Ring of Power: A Band of Peptidergic Midbrain Neurons that Binds Motivation

Abstract

Bibliographical note

Keywords

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