Risk of Latent Tuberculosis Reactivation after Hematopoietic cell Transplantation

Matthew P. Cheng, Amanda E. Kusztos, Tyler D. Bold, Vincent T. Ho, Brett E. Glotzbecker, Candace Hsieh, Meghan A. Baker, Lindsey R. Baden, Sarah P. Hammond, Francisco M. Marty

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

There were no cases of tuberculosis in a cohort of 2531 patients who underwent hematopoietic cell transplantation from 2010 to 2015 after 7323 person-years of follow up (95% confidence interval [CI], 0.0-0.05 cases/100 person-years), including 29 (1.15%) patients with untreated latent tuberculosis after 89 person-years of follow-up (95% CI, 0.0-4.06 cases/100 person-years).

Original languageEnglish (US)
Article numberciz048
Pages (from-to)869-872
Number of pages4
JournalClinical Infectious Diseases
Volume69
Issue number5
DOIs
StatePublished - Aug 16 2019

Bibliographical note

Funding Information:
Financial support. M. P. C. receives salary support from a postdoctoral training grant, provided by the Fonds de recherche Santé Québec.

Funding Information:
Potential conflicts of interest. This article was prepared as part of routine work. S. P. H. reports research funding from Merck. All other authors report no potential conflicts. The authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

Keywords

  • LTBI
  • Mycobacterium tuberculosis
  • TB
  • allogeneic
  • hematopoietic cell transplantation

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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