Robust antimicrobial compounds and polymers derived from natural resin acids

Jifu Wang, Yung Pin Chen, Kejian Yao, Perry A. Wilbon, Wujie Zhang, Lixia Ren, Juhua Zhou, Mitzi Nagarkatti, Chunpeng Wang, Fuxiang Chu, Xiaoming He, Alan W. Decho, Chuanbing Tang

Research output: Contribution to journalArticlepeer-review

107 Scopus citations

Abstract

We report novel robust resin acid-derived antimicrobial agents that exhibit excellent antimicrobial activities against a broad spectrum of bacteria (6 Gram-positive and 7 Gram-negative) with selective lysis of microbial membranes over mammalian membranes. Our results indicate that hydrophobicity and unique structures of resin acids can be determining factors in dictating the antimicrobial activity.

Original languageEnglish (US)
Pages (from-to)916-918
Number of pages3
JournalChemical Communications
Volume48
Issue number6
DOIs
StatePublished - Dec 14 2012

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