Robust detection and control of bubble activity during high intensity focused ultrasound ablation

Andrew Casper, Alyona Haritonova, Elias Wilken-Resman, Emad S Ebbini

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

We present results from a real-time ultrasound-guided focused ultrasound platform designed to monitor and control bubble activity. A single element transducer is used in a dual-mode fashion to interleave HIFU therapy with imaging pulses. Use of the same element for both therapy and monitoring creates an inherent alignment between the imaging focus and the therapy focus. Field programmable gate arrays (FPGA) control the signal generation and echo reception enabling real-time data processing to detect and control bubble activity with microsecond latency. Results are presented from in vitro experiments in swine liver and bovine cardiac tissue demonstrating the ability to detect bubble activity and control lesion growth at intensities up to 15 kW/m2.

Original languageEnglish (US)
Title of host publication2012 IEEE International Ultrasonics Symposium, IUS 2012
Pages2615-2618
Number of pages4
DOIs
StatePublished - Dec 1 2012
Event2012 IEEE International Ultrasonics Symposium, IUS 2012 - Dresden, Germany
Duration: Oct 7 2012Oct 10 2012

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Other

Other2012 IEEE International Ultrasonics Symposium, IUS 2012
CountryGermany
CityDresden
Period10/7/1210/10/12

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