Role of endothelial-derived nitric oxide in normal and hypertensive pulmonary vasculature

S. Archer; V. Hampl; Z. McKenzie; D. Nelson; J. Huang; P. J. Shultz; Edward K Weir

doi:10.1055/s-2007-1006361

Role of endothelial-derived nitric oxide in normal and hypertensive pulmonary vasculature

S. Archer, V. Hampl, Z. McKenzie, D. Nelson, J. Huang, P. J. Shultz, Edward K Weir

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

The role of EDNO in the PHT has been primarily evaluated in animals, with few human studies. Most research has focused on the chronic hypoxic form of PHT. With these limitations in mind, we conclude that basal pulmonary EDNO synthesis is preserved or increased in PHT. Although this EDNO up-regulation seems to reduce the severity of PHT, its relative importance among other modulating factors remains to be established.

Original language	English (US)
Pages (from-to)	179-189
Number of pages	11
Journal	Seminars in Respiratory and Critical Care Medicine
Volume	15
Issue number	3
DOIs	https://doi.org/10.1055/s-2007-1006361
State	Published - 1994
Externally published	Yes

Access

10.1055/s-2007-1006361

OpenUrl availability

Full text

Cite this

@article{dbf0a68a6e14466494d8a4c368fdd995,

title = "Role of endothelial-derived nitric oxide in normal and hypertensive pulmonary vasculature",

abstract = "The role of EDNO in the PHT has been primarily evaluated in animals, with few human studies. Most research has focused on the chronic hypoxic form of PHT. With these limitations in mind, we conclude that basal pulmonary EDNO synthesis is preserved or increased in PHT. Although this EDNO up-regulation seems to reduce the severity of PHT, its relative importance among other modulating factors remains to be established.",

author = "S. Archer and V. Hampl and Z. McKenzie and D. Nelson and J. Huang and Shultz, {P. J.} and Weir, {Edward K}",

year = "1994",

doi = "10.1055/s-2007-1006361",

language = "English (US)",

volume = "15",

pages = "179--189",

journal = "Seminars in Respiratory and Critical Care Medicine",

issn = "1069-3424",

publisher = "Thieme Medical Publishers",

number = "3",

}

TY - JOUR

T1 - Role of endothelial-derived nitric oxide in normal and hypertensive pulmonary vasculature

AU - Archer, S.

AU - Hampl, V.

AU - McKenzie, Z.

AU - Nelson, D.

AU - Huang, J.

AU - Shultz, P. J.

AU - Weir, Edward K

PY - 1994

Y1 - 1994

N2 - The role of EDNO in the PHT has been primarily evaluated in animals, with few human studies. Most research has focused on the chronic hypoxic form of PHT. With these limitations in mind, we conclude that basal pulmonary EDNO synthesis is preserved or increased in PHT. Although this EDNO up-regulation seems to reduce the severity of PHT, its relative importance among other modulating factors remains to be established.

AB - The role of EDNO in the PHT has been primarily evaluated in animals, with few human studies. Most research has focused on the chronic hypoxic form of PHT. With these limitations in mind, we conclude that basal pulmonary EDNO synthesis is preserved or increased in PHT. Although this EDNO up-regulation seems to reduce the severity of PHT, its relative importance among other modulating factors remains to be established.

UR - http://www.scopus.com/inward/record.url?scp=0028232034&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028232034&partnerID=8YFLogxK

U2 - 10.1055/s-2007-1006361

DO - 10.1055/s-2007-1006361

M3 - Review article

AN - SCOPUS:0028232034

SN - 1069-3424

VL - 15

SP - 179

EP - 189

JO - Seminars in Respiratory and Critical Care Medicine

JF - Seminars in Respiratory and Critical Care Medicine

IS - 3

ER -

Role of endothelial-derived nitric oxide in normal and hypertensive pulmonary vasculature

Abstract

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this